| 產(chǎn)品編號 | bsm-61480R |
| 英文名稱 | Profilin 1 Recombinant Rabbit mAb |
| 中文名稱 | 前纖維蛋白1重組兔單抗 |
| 別 名 | Actin binding protein; ALS18; Epididymis tissue protein Li 184a; PFN 1; Pfn; PFN1; Profilin1; ProfilinI. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-200,IHC-F=1:100-200,IF=1:50-200,Flow-Cyt=1:50-100,ICC/IF=1:50-200,IP=1:20-50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 15 kDa |
| 檢測分子量 | 15 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Profilin 1: 100-140 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. SWISS: P07737 Gene ID: 5216 前纖維蛋白(profilin)是一種低分子量的肌動蛋白結(jié)合蛋白, 前纖維蛋白除了能與肌動蛋白結(jié)合之外,在分子間相互作用的復(fù)雜網(wǎng)絡(luò)中還起到一個控制中心的作用。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with Profilin 1 monoclonal antibody, unconjugated (bsm-61480R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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