| 產(chǎn)品編號(hào) | bsm-61499R |
| 英文名稱 | TLR9 Recombinant Rabbit mAb |
| 中文名稱 | Toll樣受體9重組兔單抗 |
| 別 名 | CD289; TLR9; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 116 kDa |
| 檢測(cè)分子量 | 130 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human TLR9: 400-550/1032 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides.Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. SWISS: Q9NR96 Gene ID: 54106 Toll樣受體-9(Toll-like receptor 9,TLR9)是哺乳動(dòng)物TLRs家族中一員,作為細(xì)胞表面的天然模式識(shí)別受體,主要參與免疫刺激序列(CpG序列)激活免疫細(xì)胞的信號(hào)傳導(dǎo),從而在天然抗感染免疫及聯(lián)系天然免疫和獲得性免疫中發(fā)揮重要作用。 |
| 產(chǎn)品圖片 |
Western blot analysis of Raji cell lysate. Using TLR9 (bsm-61499R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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