| 產(chǎn)品編號 | bsm-62187R |
| 英文名稱 | Phospho-GluR1(Ser831) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化谷氨酸受體1重組兔單抗 |
| 別 名 | GLUR 1; GLUR A; AMPA 1; AMPA selective glutamate receptor 1; GluA1; GLUH1; GluR K1; GLUR1; GLURA; GluRK1; Glutamate receptor 1; Glutamate receptor ionotropic AMPA 1; Glutamate receptor ionotropic; Glutamate receptor, ionotropic, AMPA 1; Gria1; HBGR1. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 102 kDa |
| 檢測分子量 | 102 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human GluR1 around the phosphorylation site of S831: PQQ-pS-INE (全長906aa) p831位點(diǎn)需要減掉18aa的信號肽。 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity. SWISS: P42261 Gene ID: 2890 NMDAR1又稱GluR1 (Glutamate Receptor 1)近年實(shí)驗(yàn)研究發(fā)現(xiàn)，許多NMDAR拮抗藥均具有鎮(zhèn)痛活性，表明NMDAR在痛覺傳遞中具有重要作用，這為新型鎮(zhèn)痛藥的研究開發(fā)提供了新的作用靶點(diǎn)。 |
