| 產(chǎn)品編號(hào) | IHC0528 |
| 英文名稱 | GAD65 Ready-To-Use IHC Kit |
| 中文名稱 | 谷氨酸脫羧酶-65即用型免疫組化試劑盒 |
| 別 名 | 6330404F12Rik; GAD(65); Gad-2; GAD2; GAD65 |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
GAD65 (glutamic acid decarboxylase-65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD. SWISS: P48320 Gene ID: 14417 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Mouse brain tissue slide using IHC0528 (GAD65 Kit).
Immunohistochemical analysis of paraffin embedded Rat brain tissue slide using IHC0528 (GAD65 Kit).
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