| 產(chǎn)品編號(hào) | IHC0547 |
| 英文名稱 | IDH1 Ready-To-Use IHC Kit |
| 中文名稱 | 異檸檬酸脫氫酶1即用型免疫組化試劑盒 |
| 別 名 | AI314845; AI788952; E030024J03Rik; HEL-216; HEL-S-26; Id-1; IDCD; IDH; Idh-1; IDH1; IDP; IDPC; PICD |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. SWISS: O75874 Gene ID: 3417 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Mouse stomach tissue slide using IHC0547 (IDH1 Kit).
Immunohistochemical analysis of paraffin embedded Human gastric fundus tissue slide using IHC0547 (IDH1 Kit).
Immunohistochemical analysis of paraffin embedded Human gastric cancer tissue slide using IHC0547 (IDH1 Kit).
Immunohistochemical analysis of paraffin embedded Rat stomach tissue slide using IHC0547 (IDH1 Kit).
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