| 產(chǎn)品編號 | IHC0551R |
| 英文名稱 | Rat GRP94 Ready-To-Use IHC Kit |
| 中文名稱 | 大鼠葡萄糖調(diào)節(jié)蛋白94即用型免疫組化試劑盒 |
| 別 名 | ECGP; endoplasmin; ERp99; GP96; GRP94; HEL-S-125m; HEL35; HSP90B1; HSPC4; TA-3; Targ2; Tra-1; TRA1 |
| 克 隆 號 | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells. SWISS: P14625 Gene ID: 7184 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Rat stomach tissue slide using IHC0551R (Rat GRP94 Kit).
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