| 產(chǎn)品編號(hào) | IHC0589H |
| 英文名稱 | Human c-Met Ready-To-Use IHC Kit |
| 中文名稱 | 人肝細(xì)胞生長(zhǎng)因子受體即用型免疫組化試劑盒 |
| 別 名 | c-Met; DFNB97; AUTS9; c met; D249; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF/SF receptor; HGFR; MET; Met proto oncogene tyrosine kinase; MET proto oncogene; receptor tyrosine kinase; Met proto-oncogene (hepatocyte growth factor receptor); Met proto-oncogene; Met protooncogene; MET_HUMAN; Oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing. SWISS: P08581 Gene ID: 4233 |
| 產(chǎn)品圖片 |
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Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0589H (Human c-Met Kit).
Immunohistochemical analysis of paraffin embedded Human lung cancer tissue slide using IHC0589H (Human c-Met Kit).
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