| 產(chǎn)品編號 | IHC0614H |
| 英文名稱 | Human STING1 Ready-To-Use IHC Kit |
| 中文名稱 | 人跨膜蛋白173即用型免疫組化試劑盒 |
| 別 名 | SAVI; STING1; TMEM173; endoplasmic reticulum IFN stimulator; Endoplasmic reticulum interferon stimulator; ERIS; FLJ38577; hMITA; hSTING; Mediator of IRF3 activation; MITA; Mitochondrial mediator of IRF3 activation; MPYS; N terminal methionine proline tyrosine serine plasma membrane tetraspanner; NET23; Stimulator of interferon genes; Stimulator of interferon genes protein; STING; TM173_HUMAN; Tmem173; Transmembrane protein 173 |
| 克 隆 號 | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human prostate cancer tissue slide using IHC0614H (Human STING1 Kit).
Immunohistochemical analysis of paraffin embedded Human ovarian cancer tissue slide using IHC0614H (Human STING1 Kit).
腸癌.jpg)
Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0614H (Human STING1 Kit).
腸.jpg)
Immunohistochemical analysis of paraffin embedded Human colon tissue slide using IHC0614H (Human STING1 Kit).
Immunohistochemical analysis of paraffin embedded Human tonsil tissue slide using IHC0614H (Human STING1 Kit).
|
